科学研究情况简介 |
【近5年来主要研究课题】 1.高性能三维石墨烯材料的构筑、功能化及在生物分析中的应用。 2.上转换发光材料与石墨烯量子点复合，及对癌症的诊疗一体化研究。 3.生物快速检测与药物光控释放。 4.环状短RNA用于肿瘤靶向治疗的研究。 【近5年来主持项目】 1.教育部直属高校科研项目，基于宫颈癌精准医疗的石墨烯量子点-稀土上转换纳米载药体系研究 2.企业横向课题两项 【近5年来代表性论文】 1.Li Ruiyi, Li Zaijun, Sun Xiulan, Ji Jan, Liu Lin, Gu Zhiguo, Wang Guangli. Graphene quantum dot-rare earth upconversion nanocages with extremely high efficiency of upconversion luminescence, stability and drug loading towards controlled delivery and cancer theranostics, Chemical Engineering Journal, 2020, 382:122992. 2.Li Ruiyi, Pu Tinling, Chu Hongxia, Shi Jinsong, Li Zaijun. Electrochemical detection of cancer cells in human blood using folic acid and glutamic acid-functionalized graphene quantum dot-palladium@gold as redox probe with excellent electrocatalytic activity and target recognition, Sensors & Actuators: B. Chemical, 2020, 309:127709. 3.Peng Yuanfeng,Li Ruiyi（共同第一作者）, Xie Qingqing, Chen Xiaofen, Yang Yongqiang, Li Zaijun. Electrochemical detection of Mycobacterium tuberculosis IS6110 gene T fragments based on the gold nanocrystals with uniform morphology and highly exposed high-index facets and target DNA-induced recycling amplification, Sensors & Actuators: B. Chemical, 2020, 314:128061. 4.Ling Liu,Ruiyi Li（共同第一作者）, Guangli Wang, Zhiguo Gu, Zaijun Li. Graphene quantum dots-NaYF4:Yb,Er hybrid with significant enhancement of upconversion emission for fluorescent detection of carcinoembryonic antigen with exonuclease III-aided target recycling amplification, Sensors & Actuators: B. Chemical, 2019, 285:453-461. 5.Ruiyi Li,Fangchao Cui, Haiyan Zhu, Xiulan Sun, Zaijun Li. Electrochemical sensor for detection of cancercell based on folic acid and octadecylamine-functionalized graphene aerogel microspheres, Biosensors and Bioelectronics, 2018, 119:156-162. 6.Ruiyi Li, Ling Liu, Hongxia Bei, Zaijun Li. Nitrogen-doped multiple graphene aerogel/gold nanostar as the electrochemical sensing platform for ultrasensitive detection of circulating free DNA in human serum, Biosensors and Bioelectronics, 2016, 79:457-466. 7.Ruiyi Li,Zaijun Li, Guangli Wang, Zhiguo Gu. Octadecylamine-functionalized graphene vesicles basedvoltammetric sensing of hydroquinone, Sensors & Actuators: B. Chemical, 2018, 276:404-412. 8.Ruiyi Li,Ling Liu, Haiyan Zhu, Zaijun Li. Synthesis of gold-palladium nanowaxberries/dodecylaminefunctionalized graphene quantum dots-graphene micro-aerogel for voltammetric determination of peanut allergen Ara h 1, Analytica Chimica Acta, 2018, 1008:38-47. 9.Ruiyi Li,Haiyan Zhu, Zaijun Li, Junkang Liu. Electrochemical determination of acetaminophen using a glassy carbon electrode modified with a hybrid material consisting of graphene aerogel and octadecylaminefunctionalized carbon quantum dots, Microchimica Acta, 2018, 185(2):145. 10.Ruiyi Li, Xuan Wang, Zaijun Li, Haiyan Zhu, Junkang Liu. Folic acid-functionalized graphene quantum dots with tunable fluorescence emission for cancer cell imaging and optical detection of Hg2+, New Journal of Chemistry, 2018, 42:4352-4360. 11.Ruiyi Li,Sili Qing, Zhangyi Li, Ling Liu, Zaijun Li. Histidine-functionalized graphene quantum dot-graphene micro-aerogel based voltammetric sensing of dopamine, Sensors & Actuators B Chemical, 2017, 250:372-382. 12.Ruiyi Li,Tingting Yang, Zaijun Li, Zhiguo Gu, Guangli Wang, Junkang Liu. Synthesis of palladium@ gold nanoalloys/nitrogen and sulphur-functionalized multiple graphene aerogel for electrochemical detection of dopamine, Analytica Chimica Acta, 2017, 954:43-51. 13.Ruiyi Li,Ling Liu, Zaijun Li, Zhiguo Gu, Guangli Wang, Junkang Liu. Graphene micro-aerogel based voltammetric sensing of p-acetamidophenol, Microchimica Acta, 2017, 184(5):1-10. 14.Ruiyi Li,Zaijun Li, Junkang Liu. Histidine-functionalized carbon-based dot-Zinc(II) nanoparticles as a novel stabilizer for Pickering emulsion synthesis of polystyrene microspheres, Journal of Colloid & Interface Science, 2017, 493:24-31. 15.Ruiyi Li,Jiajia Wang, Ling Liu, Zaijun Li. Ultrasensitive direct detection of dsDNA using a glassy carbon electrode modified with thionin-functionalized multiple graphene aerogel and gold nanostars. Microchimica Acta, 2016, 183(5):1641-1649. 16.Ruiyi Li,Huiying Wang, Xiaoyan Zhou, Xiaoqing Liao, Xiulan Sun, Zaijun Li. d-Penicillamine and bovine serum albumin co-stabilized copper nanoclusters with remarkably enhanced fluorescence intensity and photostability for ultrasensitive detection of Ag, New Journal of Chemistry, 2016, 40(1):732-73. 17.Ruiyi Li,Jun Chen, Xiaoyan Zhou, Zaijun Li, Junkang Liu. Fabrication of zinc-histidine-functionalized graphene quantum dot framework amphiphilic nanoparticles and application in the synthesis of polystyrene microspheres for adsorption of Cu2+by Pickering emulsion polymerization, Rsc Advances, 2016, 6(104). 【近5年主要授权专利】 1.荧光增强型石墨烯量子点-下转换稀土氟化物复合材料，李在均，刘玲，李瑞怡，ZL 2018 1 0218688.9 2.一种功能化石墨烯气凝胶微球的制备方法，李在均，李瑞怡，ZL 2018 1 0218703.X 【主要奖励】 李在均，瞿研，王光丽，顾志国，李瑞怡，蔡燕，石墨烯工业制备关键技术开发与应用，中国轻工业联合会科学技术发明奖，三等奖，2017。 |
