【近5年来主要研究课题】 1.具有血管再生和组织粘附能力的改性明胶的研发 2.可持续释放抗癌药的呼吸外科胶粘剂的研发 3.疏水改性聚乙烯醇在生物医学领域的应用研究 【近5年来代表性论文】 1.Chen X.; Mizuta R.; Fukata N.; Taguchi T., et al. Design of bio-inspired adhesive surface composed of hexanoyl group-modified gelatin and silicon nanowire.Colloids and Surfaces B: Biointerfaces2019, 178 (1), 111-119. 2.Chen X.; Taguchi T., et al. Hydrophobically modified poly(vinyl alcohol)s as antithrombogenic coating materials.Materials Science and Engineering: C 2019, 102, 289-298. 3.Chen X.; Taguchi T., et al. Injectable, non-diffusible and pre-filled bone paste composed of α-Tricalcium phosphate and hydrophobically modified poly(vinyl alcohol).Advanced Engineering Materials2019, 21 (11), 1900660. 4.Chen X.; Taguchi T., et al. Enhanced skin adhesive property of hydrophobically-modified poly(vinyl alcohol) films.ACS OMEGA2019, 5 (3), 1519-1527. 5.Shi C.#;Chen X.#; Zhang Z.; Chen Q.; Shi D.;Kaneko D.,et al.Mussel inspired bio-adhesive with multi-interactions for tissue repair.Journal of Biomaterials Science, Polymer Edition2019,31 (4), 491-503. 6.Chen X.; Taguchi T., et al. Injectable inclusion complex composed of α-cyclodextrin and hydrophobically modified poly(vinyl alcohol) as cerebral aneurysm embolization material.Polymer Journal 2020,52, 793–802. 7.Chen X.;Nishiguchi A.;Taguchi T., et al. Adhesive submucosal injection material based on the nonanal group-modified poly (vinyl alcohol)/α-cyclodextrin inclusion complex for endoscopic submucosal dissection.ACS Applied Bio Materials2020, 3 (7), 4370-4379. 8.Chen X.;Yang W.;Zhang J.;Zhang L.;Shen H.; Shi D., et al. Alkalinity triggered the degradation of polydopamine nanoparticles.Polymer Bulletin 2020 DOI:10.1007/s00289-020-03312-2. 9.Chen X.; Taguchi T., et al.Enhanced skin adhesive property of electrospun α-cyclodextrin/nonanyl group-modified poly(vinyl alcohol) inclusion complex fiber sheet.RSC Advances2021, 11, 8759-8766. 10.Chen X.; Taguchi T., et al. Enhanced Skin Adhesive Property of α-cyclodextrin/Nonanyl Group-modified Poly(vinyl alcohol) Inclusion Complex FilmCarbohydrate Polymers 2021, 263, 117993. 11.Chen X.; Taguchi T., et al.Bonding a Dental Implant and Soft Tissue Interface by Using an Adhesive Bone Paste Composed of α-Tricalcium Phosphate and α-Cyclodextrin/Nonanyl Group-Modified Poly(Vinyl Alcohol) Inclusion Complex.Colloids and Surfaces B: Biointerfaces2021, 263, 117993. 12.Ichimaru H.; Mizuno Y.;Chen X.; Nishiguchi A.;Taguchi T., et al.Prevention of pulmonary air leaks using a biodegradable tissue-adhesive fiber sheet based on Alaska pollock gelatin modified with decanyl groups.Biomaterials Science2021, 9, 861-873. 13.Mizuta R.; Mizuno Y.;Chen X.; Kurihar Y.;Taguchi T., et al.Evaluation of an octyl group-modified Alaska pollock gelatin-based surgical sealant for prevention of postoperative adhesion.Acta biomaterials2021, 121, 328-338. 14.Masuda S.; Suzuki T.; Shibata S.; Abe Y.;Chen X.; Mizuno Y.; Nishiguchi A.; Kimura H.; Matsumura N.; Iwamoto T.; Taguchi T.; Matsumoto M.; Nakamura M., et al.A novel Alaska pollock gelatin sealant shows higher bonding strength and comparable nerve regeneration than fibrin sealant in a cadaveric model and a rat model.Plastic and Reconstructive Surgery2021 【主要奖励】 日本筑波生物医学工程合作论坛2020，研究奖励奖 日本生物材料学会第41届年会，优秀研究海报奖 |
