科学研究情况简介 |
【近年来获得的学术科研成果】 近年来主要研究工作包括：1) 化学-生物法生产手性药物及中间体，2) 多酶级联催化生产精细化学品，3) 新功能生物催化剂的分子创制等。在Nature Communications (IF 11.878)、Biotechnology Advances (IF 12.831)等本研究领域权威期刊上发表SCI论文4篇，影响因子总和30.81。申请发明专利4项，其中国际专利一项(已授权)，中国专利3项(授权2项)；获得江苏省优秀专业学位硕士论文(2016)。 【近年来主要论文代表作】 [1] Song Wei, Chen Xiulai, Wu Jing, Xu Jianzhong, Zhang Weiguo, Liu Jia, Chen Jian, Liu Liming*. Biocatalytic derivatization of proteinogenic amino acids for fine chemicals. Biotechnology Advances, 2019, https://doi.org/10.1016/j.biotechadv.2019.107496. [2] Song Wei, Wang Jinhui, Wu Jing, Liu Jia, Chen Xiulai, Liu Liming*. Asymmetric assembly of high-value α-functionalized organic acids using a biocatalytic chiral-group-resetting process. Nature Communications, 2018, 9:3818. [3] Song Wei, Sun Xia, Chen Xiulai, Liu Dongxu, Liu Liming*. Enzymatic production of L-citrulline by hydrolysis of the guanidinium group of L-arginine with recombinant arginine deiminase. Journal of Biotechnology, 2015, 208:37-43. [4] Song Wei, Niu Panqing, Chen Xiulai, Liu Liming*. Enzymatic production of L-ornithine from L-arginine with recombinant thermophilic arginase. Journal of molecular catalysis B: Enzymatic, 2014, 110, 1-7. 【主要授权国家发明专利】 [1] 吴静, 宋伟, 郑凯. 一种高产维生素C-2-磷酸酯的方法. 2020-02-11, 中国, ZL201610793043.9. [2] 刘立明, 刘佳, 宋伟. 一种高效生产L-瓜氨酸的方法. 2018-05-04, 中国, ZL2015102306694. |
