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编辑: 朱劼    发布日期: 2021-02-28   来源:威廉希尔体育  
2020年
序号 论文名称 来源期刊 收录情况
1 Investigating   Adsorption/Desorption of DNA on ZIF-8 Surface by Fluorescently Labeled   Oligonucleotides Langmuir SCI
2 Simultaneous   Delivery of antimiR-21 and Doxorubicin by Graphene Oxide for Reducing   Toxicity in Cancer Therapy ACS Omega SCI
3 17D黄热病病毒在鸡胚成纤维细胞(DF-1)上的传代培养 药物生物技术 统计源期刊
4 人血清白蛋白的生物制备工艺优化 生物学杂志 CSCDE
5 融合蛋白HSA-HGF的体内抗肝纤维化活性 食品与生物技术学报 CSCDC
6 Integrating   Machine Learning-Based Virtual Screening With Multiple Protein Structures and   Bio-Assay Evaluation for Discovery of Novel GSK3 beta Inhibitors FRONTIERS   IN PHARMACOLOGY SCI
7 Theoretical   Exploring Selective-Binding Mechanisms of JAK3 by 3D-QSAR, Molecular Dynamics   Simulation and Free Energy Calculation FRONTIERS   IN MOLECULAR BIOSCIENCES SCI
8 Computational   investigation of the selectivity mechanisms of PI3K delta inhibition with   marketed idelalisib: combined molecular dynamics simulation and free energy   calculation STRUCTURAL   CHEMISTRY SCI
9 Targeting   phosphatidylinositol 3-kinase gamma (PI3Kgamma): Discovery and development of   its selective inhibitors Medicinal   research reviews SCI


2019年
序号 论文名称 来源期刊 收录情况
1 Site-specific   integration of light chain and heavy chain genes of antibody into CHO-K1   stable hot spot and detection of antibody and fusion protein expression level Preparative   Biochemistry and Biotechnology SCI
2 Discovery   of a stable expression hot spot in the genome of Chinese hamster ovary cells   using lentivirus-based random integration Biotechnology   & Biotechnological Equipment SCI
3 Theoretical   studies on the selectivity mechanisms of PI3Kδ inhibition with marketed   idelalisib and its derivatives by 3D-QSAR, molecular docking, and molecular   dynamics simulation Journal   of Molecular Modeling SCI
4 Theoretical   Studies on the Selectivity Mechanisms of Glycogen Synthase Kinase 3beta   (GSK3beta) with Pyrazine ATP-competitive inhibitors by 3D-QSAR, Molecular   Docking, Molecular Dynamics imulation and Free Energy Calculations Current   computer-aided drug design   SCI
5 Rational   Design of Novel Phosphoinositide 3-Kinase Gamma (PI3K gamma) Selective   Inhibitors: A Computational Investigation Integrating 3D-QSAR, Molecular   Docking and Molecular Dynamics Simulation CHEMISTRY   & BIODIVERSITY SCI
6 Discovery   of a novel phosphoinositide 3-kinase gamma (PI3K gamma) inhibitor against   hematologic malignancies and theoretical studies on its PI3K gamma-specific   binding mechanisms RSC   ADVANCES SCI
7 Insight   into the selective mechanism of phosphoinositide 3-kinase gamma with   benzothiazole and thiazolopiperidine gamma-specific inhibitors by in silico   approaches CHEMICAL   BIOLOGY & DRUG DESIGN SCI
8 Signal   amplification method for miR-205 assay through combining graphene oxide with   duplex-specific nuclease RSC   Advances SCI
9 RNase   H amplified RNA probe and graphene oxide system for highly sensitive   detection of (CAG)n DNA repeat sequences Nanotechnology SCI
10 A   graphene oxide fluorescent sensing platform for sensitive and specific   detecting biomarker of radiation-resistant nasopharyngeal carcinoma Bioorganic   and Medicinal Chemistry Letter SCI
11 一种新型PI3K抑制剂JN-65的抗肿瘤活性及其分子模拟机制研究 中国药科大学学报 CSCDC
12 转化生长因子βⅡ型受体胞外域融合蛋白的体内抗肝纤维化活性研究 中国药科大学学报 CSCDC

 

2018年
序号 论文名称 来源期刊 收录情况
1 SPZ1   is critical for chemoresistance and aggressiveness in drug-resistant breast   cancer cells Biochemical   Pharmacology SCI
2 Bulge   oligonucleotide as an inhibitory agent of bacterial topoisomerase I JOURNAL   OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY SCI
3 鸦胆子油的乙酯化工艺研究 中国油脂 CSCDC
4 GLP-1类似物活性检测细胞模型的建立及其功能分析 中国细胞生物学学报 CSCDC
5 雌激素受体2(ESR2)mRNA   5'非翻译区内部核糖体进入位点活性的鉴定与分析 中国生物化学与分子生物学报 CSCDC
6 Discover   Stable Expression Hot Spot in Genome of Chinese Hamster Ovary Cells Using   Lentivirus based Random Integration Method 生物工程学报 CSCDC
7 重组溶瘤痘苗病毒VG9-MnSOD的构建及其对胃癌细胞的杀伤作用 中国生物制品学杂志 CSCDE

 

2017
序号 论文名称 来源期刊 收录情况
1 TRPC5-induced   autophagy promotes drug resistance in breast carcinoma via CaMKKβ/AMPKα/mTOR   pathway Scientific   Reports SCI
2 Overexpression   of TrpC5 promotes tumor metastasis via the HIF-1α–Twist signaling pathway in   colon cancer Clinical   Science SCI
3 Inhibition   of the ubiquitin ligase activity improves the production of biologically   active fusion protein HSA-HGF in Chinese hamster ovary cells Bioengineered SCI
4 Identification   of Human UMP/CMP Kinase 1 as Doxorubicin Binding Target Using Protein   Microarray SLAS   Discovery SCI
5 UCH-L1-containing   exosomes mediate chemotherapeutic resistance tranfer in breast cancer Journal   of surgical oncology SCI
6 Inhibition   of B7-H3 reverses oxaliplatin resistance in human colorectal cancer cells Biochemical   and Biophysical Research Communications SCI
7 Paclitaxel-mediated   human aryl hydrocarbon receptor mRNA translation by an internal ribosomal   entry site-dependment mechanism Oncology   Reports SCI
8 A   simple, rapid method for evaluation of transfection efficiency based on   fluorescent dye Bioengineered SCI
9 Efficient   Expression of Stable Recombinant Human Insulin-Like Growth Factor-1 Fusion   with Human Serum Albumin in Chinese Hamster Ovary Cells Preparative   Biochemistry and Biotechnology SCI
10 Production   of Human Mutant Biologically Active Hepatocyte Growth Factor in Chinese   Hamster Ovary Cells Preparative   Biochemistry and Biotechnology SCI
11 Gemcitabine   and Doxorubicin Combination Enhance the Cytotoxic Effect to Pancreatic Cancer   Cells BxPC3 and PANC1 through UMP/CMP Kinase 1 Journal   of Biosciences and Medicines 国际学术刊物
12 肝纤维化与干细胞疗法 上海交通大学学报(医学版) CSCDC
13 信号肽对肝细胞生长因子HGF在CHO中表达及分泌的影响 中国细胞生物学学报 CSCDC
14 CMPK1蛋白与阿霉素引起的多药耐药的相关性研究 中国药理学通报 CSCDC
15 营养胁迫条件与耐药乳腺癌细胞生长优势的相关性研究 中国细胞生物学学报 CSCDC
16 骨形态发生蛋白10在中国仓鼠卵巢细胞中的表达、纯化及其生物活性 中国生物制品学杂志 CSCDE

 

2016
序号 论文名称 来源期刊 收录情况
1 Chemotherapy enhances tumor vascularization via Notch signaling-mediated formation of tumor-derived endothelium in breast cancer BIOCHEMICAL PHARMACOLOGY SCI
2 Translocation of PKG1 alpha acts on TRPV4-C1 heteromeric channels to inhibit endothelial Ca2+ entry ACTA PHARMACOLOGICA SINICA SCI
3 La Autoantigen Induces Ribosome Binding Protein 1 (RRBP1) Expression through Internal Ribosome Entry Site (IRES)-Mediated Translation during Cellular Stress Condition INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES SCI
4 内部核糖体进入位点(IRES)调控细胞血清饥饿应激条件下PRDM13的翻译 中国生物化学与分子生物学报 CSCDC
5 转录因子GATA3 mRNA 5'非翻译区内部核糖体进入位点的活性 中国细胞生物学学报 CSCDC
6 循环包装回收技术在筛选肝癌细胞相关耐药基因中的应用 生物工程学报 CSCDC
7 锌指蛋白转录抑制因子14 5'非翻译区内部核糖体进入位点的活性 中国生物制品学杂志 CSCDE
8 TrpC5 regulates differentiation through the Ca2+/Wnt5a signalling pathway in colorectal cancer Clinical Science SCI
9 Methylation of Notch3 modulates chemoresistance via P-glycoprotein European Journal of Pharmacology SCI
10 Notch3 negatively regulates chemoresistance in breast cancers Tumor Biology SCI
11 Inhibition of the ubiquitin ligase activity improves the production of biologically active fusion protein HSA-HGF in Chinese hamster ovary cells Bioengineered SCI
12 A simple, rapid method for evaluation of transfection efficiency based on fluorescent dye Bioengineered SCI
13 ATF2 translation is induced under chemotherapeutic drug-mediated cellular stress via an IRES-dependent mechanism in human hepatic cancer Bel7402 cells Oncology Letters SCI
14 Theoretical Studies on the Selective Mechanisms of GSK3β and CDK2 by Molecular Dynamics Simulations and Free Energy Calculations Chemical Biology & Drug Design  SCI
15 人血清白蛋白-干扰素α2b 融合蛋白在CHO细胞中的表达 中国生物工程杂志 CSCDC
16 3种撞击器法测定吸入气雾剂体外沉积性质的差异性研究 国际药学研究杂志 CSCDC
17 表达IFNα2b-HSA融合蛋白的CHO细胞培养基优化及发酵放大 化工进展 CSCDC

   

2015年
序号 论文名称 来源期刊 收录情况
1 Enhancement of vascular endothelial growth factor release in long-term drug-treated breast cancer via transient receptor potential channel 5-Ca2+-hypoxia-inducible factor 1 alpha pathway PHARMACOLOGICAL RESEARCH SCI
2 JF-305, a pancreatic cancer cell line is highly sensitive to the PARP inhibitor olaparib ONCOLOGY LETTERS SCI
3 Efficient expression of glucagon-like peptide-1 analogue with human serum albumin fusion protein in Pichia pastoris using the glyceraldehyde-3-phosphate dehydrogenase promoter Biotechnology and Bioprocess Engineering SCI
4 Expression of a glucagon-like peptide-1 analogue, as a therapeutic agent for type II diabetes, with enhanced bioactivity and increased N-terminal homogeneity in Pichia pastoris Biotechnol Lett SCI
5 Antitumor and anti-angiogenic activity of the recombinant human disintegrin domain of A disintegrin and metalloproteinase 15 MOLECULAR MEDICINE REPORTS SCI
6 Inhibition of Transient Receptor Potential Channel 5 Reverses 5-Fluorouracil Resistance in Human Colorectal Cancer Cells J BIOL CHEM SCI
7 beta-Catenin expression is regulated by an IRES-dependent mechanism and stimulated by paclitaxel in human ovarian cancer cells BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS SCI
8 The 5 '-UT'R of DDB2 harbors an IRES element and upregulates translation during stress conditions GENE SCI
9 Crystallization and preliminary X-ray diffraction analysis of an endo-1,4-beta-D-glucanase from Aspergillus aculeatus F-50 ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS SCI
10 转录激活因子 1( ATF1) 内部核糖体进入位点的鉴定及活性分析 中国生物化学与分子生物学报 CSCD
11 PARP-1体外活性测定方法的建立及其应用 Journal of Food Science and Biotechnology CSCD
12 毕赤酵母系统来源的重组人血清白蛋白的制备及初步晶体学分析 Journal of Food Science and Biotechnology CSCD
13 UPLC / Q-TOF-MS 法检测 2 种中成药中土霉素、马来酸氯苯那敏和醋酸泼尼松 中成药 CSCD
14 Coniothyrium minitans菌株JN-CM摇瓶制种工艺的初步研究 Industrial Microbiology CSCD
15 Breast cancer resistance protein (BCRP)-containing circulating microvesicles contribute to chemoresistance in breast cancer ONCOLOGY LETTERS SCI
16 利用 GAP 启动子在毕赤酵母中表达与纯化 GLP-1 类似物 中国生物工程杂志 CSCD
17 重组凝血因子Ⅶ表达和合成机制的研究进展 中国药科大学学报 CSCD
18 液相色谱-四级杆-飞行时间质谱联用技术在药物分析中的应用 中南药学 统计源
19 建立应急检验模型快速筛查及确证片剂中添加的枸橼酸西地那非 中国药事 统计源
2014年
序号 论文名称 来源期刊 收录情况
1 Essential role for TrpC5-containing extracellular vesicles in breast cancer with chemotherapeutic resistance PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA SCI
2 MiR-489 regulates chemoresistance in breast cancer via epithelial mesenchymal transition pathway FEBS LETTERS SCI
3 Microvesicles mediate transfer of P-glycoprotein to paclitaxel-sensitive A2780 human ovarian cancer cells, conferring paclitaxel-resistance EUROPEAN JOURNAL OF PHARMACOLOGY SCI
4 Tumor endothelial expression of P-glycoprotein upon microvesicular transfer of TrpC5 derived from adriamycin-resistant breast cancer cells BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS SCI
5 Cost-effective production of recombinant human interleukin 24 by lactose induction and a two-step denaturing and one-step refolding method JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY SCI
6 Vasonatrin peptide stimulates both of the natriuretic peptide receptors, NPRA and NPRB BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS SCI
7 Molecular Dynamics and Bioactivity of a Novel Mutated Human Parathyroid Hormone TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH SCI
8 微囊藻毒素-LR 超灵敏均相免疫分析方法的建立与优化 中国药理学与毒理学杂志 CSCD
9 rhddADAM15抑制肝癌细胞Bel-7402增殖的作用研究 中国细胞生物学学报 CSCD
10 融合蛋白CBD SPAZ基因的构建、表达与活性鉴定 生物加工过程 CSCD
11 新型抗体结合蛋白CBD-SPG的设计与表达 工业微生物 CSCD
12 人血清白蛋白-血管钠肽融合蛋白在毕赤酵母中的表达 工业微生物 CSCD
13 Methylation-regulated miR-149 modulates chemoresistance by targeting GlcNAc N-deacetylase/N-sulfotransferase-1 in human breast cancer FEBS J SCI
14 A 20-gene signature in predicting the chemoresistance of  breast cancer to taxane-based chemotherapy MOL BIOSYST SCI
15 Inhibition of Transient Receptor Potential Channel 5 Reverses 5-Fluorouracil Resistance in Human Colorectal Cancer Cells J BIOL CHEM SCI
16 A Methylation-Based Regulatory Network for MicroRNA 320a in
           Chemoresistant Breast Cancer
MOLECULAR PHARMACOLOGY SCI
17 The Effects of Fusion Structure on the Expression and Bioactivity of Human Brain Natriuretic Peptide (BNP) Albumin Fusion Proteins Current Pharmaceutical Biotechnology SCI
18 Recombinant human inerleukin 24 reverses Adriamycin resistance in a human breast cancer call line PHARMACOL REP SCI
19 Electrostatic potentials of camptothecin and its analogues Theor Chem Acc SCI
20 Develoment and Characterization of Monoclonal Antibodies Against Pancreatic Cancer Marker Hippocalcin-like 1 Protein MONOCLONAL ANTIBODIES IN IMMUNODIAGNOSIS AND IMMUNOTHERAPY 国外期刊
21 A Coventional Method for Fermentation and Purification of Recombinant Human Interleukin 24 from E. coli. International Journal of Pharma Research & Review 国外期刊
22 The Analysis of Abnormal Precipitation Phenomenon in Screening Crystallization Condition of Recombinant Human Serum Albumin in Pichia Pastoris Sci-Afric Journal of Acientific Issues 国外期刊
2013年
序号 论文名称 来源期刊 收录情况
1 Anti-angiogenesis effect of trichosanthin and the underlying mechanism  Biochemical and Biophysical Research Communications SCI
2 Functional Role of TRPV4-KCa2.3 Signaling in Vascular Endothelial Cells in Normal and Streptozotocin-Induced Diabetic Rats Hypertension SCI
3 Recombinant disintegrin domain of ADAM15 inhibits the proliferation and migration of Bel-7402 cells Biochemical and Biophysical Research Communications SCI
4 Acquisition of paclitaxel resistance via PI3K?dependent epithelial?mesenchymal transition in A2780 human ovarian cancer cells Oncology Report SCI
5 Cost-effective production of recombinant human interleukin 24 by lactose induction and a two-step denaturing and one-step refolding method Journal of Industrial Microbiology & Biotechnology SCI
6 A2780 human ovarian cancer cells with acquired paclitaxel resistance display cancer stem cell properties Oncology Letters SCI
7 耐阿霉素人乳腺癌细胞MCF-7/ADM钙稳态失调及其机制研究 中国药理学通报 CSCD
8 重组人ADAM15去整合素区域蛋白与人血清白蛋白融合蛋白的表达及其活性 中国生物制品学杂志 CSCD
9 钠尿肽受体的结构特征及信号转导机制 中国科学:生命科学 CSCD
10 重组人白细胞介素2-人血清白蛋白融合蛋白的液态稳定性 食品与生物技术学报 CSCD
11 全长PTH(1-34)-HSA融合蛋白在毕赤酵母中的表达及其活性 中国生物制品学杂志 CSCD
12 重组人血管内皮生长因子165b在毕赤酵母中的表达及纯化 中国生物制品学杂志 CSCD
13 PI3K抑制剂LY294002抑制人卵巢癌耐紫杉醇细胞的增殖与迁移 中国药理学通报 CSCD
14 hPARP1酶在杆状病毒/昆虫细胞中的高表达及快速纯化 生物工程学报 CSCD
15 细胞穿膜肽TAT与小鼠干细胞转录因子Oct4融合表达及纯化 食品与生物技术学报 CSCD
16 BNP在不同缓冲体系中的血管舒张功能评价 食品与生物技术学报 CSCD
17 人白介素24(IL-24)的表达与纯化及其初步活性评价 药物生物技术 统计源
18 α-1,6-甘露糖转移酶(Och1p)缺陷型突变株毕赤酵母X33生长条件优化 工业微生物 CSCD
2012年
序号 论文名称 来源期刊 收录情况
1 Transient receptor potential channel TRPC5 is essential for P-glycoprotein induction in drug-resistant cancer cells P NATL ACAD SCI USA SCI
2 Expression and purification of recombinant human serum albumin fusion protein with VEGF165b in Pichia pastoris PROTEIN EXPRESSION AND PURIFICATION SCI
3 Luteolin inhibits pyrogallol-induced apoptosis through the extracellular signal-regulated kinases signaling pathway FEBS Journal(FASEB J)  SCI
4 Apigenin, a plant-derived flavone, activates transient receptor potential vanilloid 4 cation channel British Journal of Pharmacology(BRIT J PHARMACOL) SCI
5 Anti-angiogenesis effect of trichosanthin and the underlying mechanism Biochemical and Biophysical Research Communications SCI
6 Total flavonoids of Flos Chrysanthemi protect arterial endothelial cells against oxidative stress Journal of Ethnopharmacology.  SCI
7 人甲状旁腺激素(1-34)突变蛋白的设计与活性验证 药学学报 CSCD
8 双启动子双报告基因真核表达质粒的构建及表达 中国生物制品学杂志 CSCD
9 重组人血清白蛋白-干扰素β融合蛋白的分离纯化及质控方法的建立 中国生物制品学杂志 CSCD
10 人乳腺癌细胞及其耐药细胞转录因子表达的差异 中国药理学通报 CSCD
11 Therapeutic Applications of Interleukin 24 (IL24) A Review Tropical Journal of Pharmaceutical Research  SCI
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