Academic Career:
Apr. 2017-Dec.2017 Visiting Professor, State Key Laboratory of Coordination Chemistry, School of
Chemistry and Chemical Engineering, Nanjing University (Prof. Dr. Zhuangzhi Shi)
Jan. 2017-Present Associate Professor, School of Pharmaceutical Sciences, Jiangnan University
Oct. 2014-Dec. 2016 Associate Professor, School of Biotechnology, Jiangnan University
Education:
Oct. 2013-Sep. 2014 Postdoc. (Prof. Dr. Dieter Enders), Institute of Organic Chemistry, RWTH Aachen
University, Aachen, Germany. (Organic Chemistry)
Sep. 2009-Sep. 2013 Ph.D. (Prof. Dr. Carsten Bolm), Institute of Organic Chemistry, RWTH Aachen
University, Aachen, Germany. (Organic Chemistry)
Sep. 2006-Jun. 2009 M.S. (Prof. Dr. Qiuan Wang), College of Chemistry Chemical Engineering, Hunan
University. (Organic Chemistry)
Research Field:
Synthetic methodology; Synthesis of heterocycles; Sugar chemistry; Medicinal chemistry
Selected Publications:
1. S. Zhu, K. Shi, H. Zhu, Z.-K. Jia, X.-F. Xia, D. Wang, L.-H. Zou*, Org. Lett. 2020, 22, 1504-1509. Copper-catalyzed annulation or homocoupling of sulfoxonium ylides: synthesis of 2,3-diaroylquinolines or α,α,β-tricarbonyl sulfoxonium ylides.
2. L.-H. Zou*, H. Zhu, S. Zhu, K. Shi, C. Yan, P.-G. Li, J. Org. Chem. 2019, 84, 12301-12313. Copper-catalyzed ring-opening/reconstruction of anthranils with oxo-compounds: synthesis of quinoline derivatives.
3. P.-G. Li, C. Yan, S. Zhu, S.-H. Liu, L.-H. Zou*, Org. Chem. Front. 2018, 5, 3464-3468. Direct construction of benzimidazo[1,2-c]quinazolin-6-ones via metal-free oxidative C-C bond cleavage.
4. L.-H. Zou*, C. Zhao, P.-G. Li, Y. Wang, J. Li*, J. Org. Chem. 2017, 82, 12892-12898. Transition-metal-free C−S bond formation: synthesis of polysubstituted diaryl sulfides and alfa-thioarylcarbonyl compounds.
5. L.-H. Zou*, M. Fan, L. Wang*, C. Liu*, Chin. Chem. Lett. 2019, doi: 10.1016/j.cclet.2019.12.016. Hetero diacylation of 1,1-diborylalkanes: practical synthesis of 1,3-diketones.
6. L.-H. Zou*, C. Yan, K. Shi, L. Su, S. Zhu, Z.-K. Jia, Q. Wang*, Eur. J. Org. Chem. 2019, doi: 7725-7729. Copper-catalyzed C–C bond cleavage/double cyclization of α-ketoamides with o-phenylene diamines: synthesis of benzimidazo[1,2-c]quinazolin-6-ones.
7. P.-G. Li, H. Zhu, M. Fan, C. Yan, K. Shi, X.-W. Chi, L.-H. Zou*, Org. Biomol. Chem. 2019, 17, 5902-5907. Copper-catalyzed coupling of anthranils and α-keto acids: direct synthesis of α-ketoamides.
8. Y. Wang, S. Zhu, L.-H. Zou*, Eur. J. Org. Chem. 2019, 2179-2201. Recent advances in direct functionalization of quinones.
9. L.-H. Zou,* Y.-C. Li, P.-G. Li, J. Zhou, Z. Wu*, Eur. J. Org. Chem. 2018, 5639-5643. Solvent-controlled α-monobromination, α,α-dibromination or imidation of 1,3-diketones with N-bromosuccinimide. (VIP paper)
10. P.-G. Li*, Y. Yang, S. Zhu, H.-X. Li, L.-H. Zou*, Eur. J. Org. Chem. 2019, 73-76. Pd-catalyzed regioselective direct double C−H arylation of 6,7-benzindoles. (VIP paper)
11. P.-G. Li, Y.-C. Li, T. Zhu, L.-H. Zou,* Z. Wu*, Eur. J. Org. Chem. 2017, 6081-6084. Hydroxysulfonylation of quinones with aryl(alkyl)sulfonyl hydrazides for the synthesis of 1,4-dihydroxy-2-aryl(alkyl)sulfonylbenzenes.
12. Z. Wu,* Y.-C. Li, W.-Z. Ding, T. Zhu, S.-Z. Liu, X. Ren, L.-H. Zou*, Asian J. Org. Chem. 2016, 5, 625-628. Copper-catalyzed regioselective sulfenylation of indoles with arylsulfonyl chlorides.
13. L.-H. Zou, A. R. Philipps, G. Raabe, D. Enders*, Chem. Eur. J. 2015, 21, 1004-1008. Asymmetric synthesis of fully substituted cyclopentane-oxindoles through an organocatalytic triple Michael domino reaction.
14. L.-H. Zou, J. Mottweiler, D. L. Priebbenow, J. Wang, J. A. Stubenrauch, C. Bolm*, Chem. Eur. J. 2013, 19, 3302-3305 (Highlighted by P. Knochel, N. M. Barl, Synfacts, 2013, 9, 0537.). Mild copper-mediated direct oxidative cross-couplings of 1,3,4-oxadiazoles with polyfluoroarenes using dioxygen as oxidant.
15. L.-H. Zou, A. J. Johansson, E. Zuidema, C. Bolm*, Chem. Eur. J. 2013, 19, 8144-8152. Mechanistic insights into the copper-catalyzed Sonogashira-Hagihara-type cross-coupling reactions: sub-mol% catalyst loadings and ligand effects.
16. L.-H. Zou, D. L. Priebbenow, L. Wang, C. Bolm*, Adv. Synth. Catal. 2013, 355, 2558-2563. Copper-catalyzed synthesis of α-thiophenyl carbonyl compounds through S-S bond cleavage and C-C bond activation.
17. L.-H. Zou, J. Reball, J. Mottweiler, C. Bolm*, Chem. Commun. 2012, 48, 11307-11309. Transition metal-free direct C-H bond thiolation of 1,3,4-oxadiazoles and related heteroarenes.
18. L.-H. Zou, Z.-B. Dong, C. Bolm*, Synlett 2012, 23, 1613-1616. Metal-free phosphorylations of 1,3,4-oxadiazoles and related heterocycles.
Contact:
Phone: +86-18352516002
E-mail: zoulianghua@jiangnan.edu.cn
