科学研究情况简介 |
【近5年来获得的学术科研成果】 主要研究方向是将动态共价键化学与生物医用材料、酶催化、生物识别等结合，开发可适应性新材料。近年来主持国家自然科学基金、江苏省自然科学基金，荣获江苏省特聘教授称号，以第一作者或通讯作者发表SCI文章20余篇，包括专业权威期刊Chemical Reviews、ACS Catalysis、Chemical Communications等，并参与部分本科生教学。 【近5年来主要研究课题】 江苏省自然科学基金青年项目 江苏省“双创”博士 国家自然科学基金青年项目 【近5年来主要论文代表作】 期刊文章： Y. Zhang†, Y. Zhang†, H. Cui, M. Barboiu*, J. Chen*. Dynameric collagen self-healing membranes with high mechanical strength for effective cell growth applications, Chem. Eur. J.2020,26, 16994. Y. Liu, Z. Xu, Q. Wang, Y. Jiang, R. Wang, S. Chen, J. Zhu,Y. Zhang*, J. Chen*. Selective regulation of RANKL/RANK/OPG pathway by heparan sulfate through the binding with estrogen receptor β in MC3T3-E1 cells.Int. J. Biol. Macromol.2020,161, 1526. M. Si, W. Zhu,Y. Zhang*, M. Barboiu*, J. Chen*. Fluorodynamers displaying tunable fluorescence on constitutional exchanges in solution and at solid film-solution interface,Chem. Eur. J. 2020,26, 10191. Y. Liu, R. Wang, S. Chen, Z. Xu, Q. Wang, P. Yuan, Y. Zhou,Y. Zhang*, J. Chen*. Heparan sulfate loaded polycaprolactone-hydroxyapatite scaffolds with 3D printing for bone defect repair.Int. J. Biol. Macromol.2020,148, 153. Y. Zhang, M. Barboiu*, O. Ramstrom*, J. Chen*. Surface-directed selection of dynamic constitutional frameworks as an optimized microenvironment for controlled enzyme activation.ACS. Catal.2020,10, 1423. Y. Zhang*, Y. Qi, S. Ulrich*, M. Barboiu*, O. Ramstrom*. Dynamic covalent polymers for biomedical applications.Mater. Chem. Front.2020, 4, 489. Y. Zhang*, Y. Zhang, O. Ramstrom*. Dynamic covalent kinetic resolution.Catal. Rev.2020,62, 66. Y. Zhang, J. Chen*. Dynamic covalent chemistry in enzyme catalysis.SCIENTIA SINICA Vitae,2019,49, 605. Y. Zhang, Y. Li, C. Su, M. Barboiu*.Dynameric frameworks with aggregation-induced emission (AIE) for selective detection of ATP.ChemPlusChem. 2018,83, 506. Yan Zhang, Eddy Petit, and Mihail Barboiu*. Multivalent dendrimers and their differential recognition of short single-stranded DNAs of various length and sequence.ChemPlusChem.2018,83, 354. Y. Zhang, C. T. Supuran, M. Barboiu*, Exponential activation of carbonic anhydrase by encapsulation in dynameric host matrices with chiral discrimination.Chem. Eur. J.2018,24, 715. Y. Zhang, W. Feng, Y. Legrand, C. Supuran, C. Su and M. Barboiu*. Dynameric host frameworks for the activation of lipase through H-bond and interfacial encapsulation.Chem. Commun.2016.52, 13768. Y. Zhang, S. Jayawardena, M. Yan, O. Ramstrom*. Enzyme classification using complex dynamic hemithioacetalsystems.Chem. Commun.,2016,52, 5053. Y. Zhang, Y. Legrand, P. Eddy, C.Supuran, M, Barboiu*. Dynamic encapsulation and activation of carbonic anhydrase in multivalent dynameric host matrixes.Chem. Commun.2016,52, 4053. Y. Zhang, Y. Legrand, A. Lee, M. Barboiu*. Ligand- and metal-driven selection of flexible adaptive dynamic host receptors.Eur. J. Org. Chem.2016, 2016, 1825. Y. Zhang, M. Barboiu*. Constitutional dynamic materials - towards natural selection of function.Chem. Rev.2016,116, 809. 书籍章节： Y. Zhangand M. Barboiu*. Self-assembly in dynamic systems. J. Atwood, eds.,Comprehensive Supramolecular Chemistry II. Elsevier,2017. 【近5年主要授权国家发明专利】 【主要奖励】 |
